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Anti-Inflammatory Steroids: Are Corticosteroids Useful in Your Practice?
1 CE Credit
You will receive 1 unit of continuing education credit upon successful completion of this course.
ADA Member: $28.00
Nonmember: $42.00
Dental Team Member: $15.00
Author:
To see the author's profile please click on their name.
Daniel Becker
Learning Objectives:
Upon completion of this course, participants should be able to do the following:
- Distinguish physiological and pharmacological effects of the glucocorticoids.
- Describe the effects of glucocorticoids on the HPA axis and relate this to the concepts of alternate day-therapy and steroid preps prior to dental treatment.
- Discuss side effects and contraindications for steroid use, distinguishing short-term from long-term therapy.
- Compare glucocorticoids in terms of potency, efficacy and side effects.
- Describe possible indications and regimens for their use in dental practice.
Abstract:
Do you prescribe or administer steroidal agents in your practice? Or do you assume that their adverse effects outweigh any potential benefit? This course will review and update your thinking on the appropriate use of glucocorticoids for prophylaxis of postoperative swelling and for the treatment of selected inflammatory conditions. Contraindications and management of chronically medicated patients also are addressed.
Outline:
COURSE OUTLINE
- Overview
- Physiological Considerations
- Anti-inflammatory Action
- Considerations for Patients
- Anti-inflammatory Action
- Use of Glucocorticoids in Dentistry
- Summary
References:
- Beirne OR, Hollander B. The effect of methylprednisolone on pain, trismus, and swelling after removal of third molars. Oral Surg Oral Med Oral Pathol. 1986; 61:134-138.
- Berne RM, Levy MN. Physiology. 3rd edition St Louis: Mosby-Year Book, Inc. 1993; 949-966.
- Bracken MB, Shepard MJ, Collins WF, at. al. A randomized controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. N Engl J Med. 1990; 20(322):1405-1411.
- Hargreaves KM, Costello A. Glucocorticoids suppress levels of immunoreactive bradykinin in inflamed tissue as evaluated by microdialysis probes. Clin Pharmacol Ther. 1990; 48:168-78.
- Montgomery MT, Hogg JP, Roberts DL, Redding SW. The use of glucocorticosteroids to lessen the inflammatory sequelae following third molar surgery. J Oral Maxillofac Surg. 1990; 48:179-187.
- Olin BR and Hebel SK, editors. Drug Facts and Comparisons. 2001 edition. St Louis: Facts and Comparisons; 2001.
- Schimmer BP, Parker KL. Adrenocorticotropic hormone; Adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and actions of adrenocortical hormones. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG Eds. Goodman and Gilmans The Pharmacological Basis of Therapeutics. 9th edition. New York: McGraw-Hill, 1996.
- Silverman S, et.al. Clinical efficacy of predisone in the treatment of patients with oral inflammatory ulcerative diseases: A study of fifty-five patients. Oral Surg Oral Med Oral Pathol. 1985; 59:360-363.
- Sisk AL, Bonnington GJ. Evaluation of methylprednisolone and flurbiprofen for inhibition of the postoperative inflammatory response. Oral Surg Oral Med Oral Pathol. 1985; 60:137-145.
- Troullos ES, Hargreaves KM, Butler DP, Dionne RA. Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus. J Oral Maxillofac Surg. 1990; 48:945-52.
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